Here are some symptoms of inadequate activity: I think this all the links below covers the above info I copy and pasted. One megadose of choline (for example 2.500 mg of Alpha GPC) could cause any problem?? Symptoms of High Acetylcholine Subdued or depressed mood Anhedonia (inability to experience pleasure) Difficulty concentrating Difficulty with higher-order or complex thought processes Mental fatigue Mental confusion Memory problems Decreased motivation Feeling overly sleepy or tired (particularly in the evening), despite adequate sleep and rest High and low acetylcholine symptoms - posted in Brain Health: How can I know if my acetylcholine is too high or too low?? ... (high blood pressure) But it is possible to have an excess of acetylcholine, especially if you are taking active measures to increase your acetylcholine levels. Acetylcholine is the chief neurotransmitter of the parasympathetic nervous system which controls automatic functions such as digestion, respiration, and heart rate. Here, we look at what acetylcholine does and describe medical conditions linked with it, … Symptoms of High Acetylcholine Levels (Symptoms/Signs of Excess Acetylcholine) Before I get into the grain of this article, I'd just like to point out that the only formal, similar article, over there on MindRenewal.US' , has been on there, on top-ranking results … This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. This neurotransmitter is found all over your brain and body, it is responsible for many of the daily automatic tasks you do every day, from blinking your eyes to taking memory from short term to long term storage.Every movement made and thought you have, is dependent on the normal production and activity of this neurotransmitter.. If your symptoms are severe, call 911 or go to the nearest emergency room right away. Symptoms and diagnosis. Your brain uses it to transmit, process, and modulate information during cognitive processing, and naturally, that’s led to investigation into the use of acetylcholine as a nootropic supplement to improve cognitive function. But, in addition to H1, earlier antihistamines can also cross into the brain and bind to receptors for acetylcholine, a neurotransmitter involved in muscle contraction and blood vessel dilation. Possible effects of high acetylcholine levels. Acetylcholine is a neurotransmitter that’s essential for cognitive function. Other symptoms include increased sweating, salivation, bronchial secretions along with miosis (constricted pupils). Acetylcholine is a neurotransmitter that plays a key role in brain and muscle function. Excess of choline is harmful? Excessively high levels of acetylcholine are rare, and often produce no symptoms before our bodies correct the imbalance. I´ve been reading different articles and the symptoms seem to be very similar. Any difference in the symptoms?? Causes and Symptoms of Excess Acetylcholine Most of the time, a neurotransmitter imbalance is a case of too little, rather than too much. As a result of cholinergic crisis, the muscles stop responding to the high synaptic levels of ACh, leading to flaccid paralysis, respiratory failure, and other signs and symptoms reminiscent of organophosphate poisoning. Too Much Acetylcholine- Signs and Symptoms of Excess Acetylcholine Too much acetylcholine is not good either, being linked with depression [ 44 ] . ? Acetylcholine is a neurotransmitter, or a chemical messenger. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP … Acetylcholine.. 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